NEW TO THIS EDITION
Chapter 19
Medical Physiology: Integration Using Clinical Cases
. Three case studies, adapted from real-life
scenarios, are presented to the student in a way that requires the student to think critically and apply what
has been learned throughout the semester to novel clinical situations.
Physiological Inquiries
These inquiries are associated with key fi gures throughout the chapters,
encouraging students to stop and think about the broader implications of what they have just learned.
Chapter 1 Homeostasis: A Framework for
Human Physiology
Introduction of the concept of dynamic constancy;
new fi gure
illustrating water distribution among body
compartments;
new fi gure
illustrating changes in blood
glucose levels during 24 hours, as an example of a
homeostatic process.
Chapter 2 Chemical Composition of the Body
Expanded discussion of free radicals and their
relationship to aging;
trans
fatty acids.
Chapter 3 Cell Structure, Protein Function,
and Metabolic Pathways
Expanded discussion of desmosomes, cadherins, and
connexins; addition of vaults to section on cellular
organelles.
Chapter 4 Movement of Molecules Across
Cell Membranes
New description and illustrations
of receptor-mediated
endocytosis and potocytosis.
Chapter 5 Control of Cells by Chemical
Messengers
Clarifi cation and expanded description of types of
receptors.
Chapter 6 Neuronal Signaling and the
Structure of the Nervous System
New Additional Clinical Examples (nicotine; multiple
sclerosis); updated, expanded discussion of mechanisms
of neurotransmitter release;
new fi gure
elaborating
autonomic neurotransmitters and their receptors.
Chapter 7 Sensory Physiology
Updated section on processing of visual signals,
including on- and off-bipolar cell pathways fat-sensitive
taste receptor;
new fi gure
demonstrating referred pain
mechanism;
new fi gure
with updated explanation of
photobleaching of cone pigments.
Chapter 8 Consciousness, The Brain,
and Behavior
Expanded discussion of the physiological functions of
sleep; ADHD and its treatment; anterograde amnesia.
Chapter 9 Muscle
New section
on Cardiac Muscle; creatine supplements
and their use in athletics.
Chapter 10 Control of Body Movement
Description of the use of deep-brain stimulation for
Parkinson disease;
new fi gure
illustrating integration of
spinal interneurons.
Updates & Additions
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