120
120
Computerized image of a ligand
(purple color) binding to its
receptor (yellow color).
Receptors
Regulation of Receptors
Signal Transduction Pathways
Pathways Initiated by Lipid-Soluble
Messengers
Pathways Initiated by Water-Soluble
Messengers
Plasma Membrane Receptors and Gene
Transcription
Cessation of Activity in Signal
Transduction Pathways
chapter
5
Control of Cells
by Chemical
Messengers
y
ou learned in Chapter 1 how
homeostatic control systems
help maintain a normal
balance of the body’s internal
environment. The operation of
control systems requires that cells be
able to communicate with each other,
often over long distances. Much of
this intercellular communication is
mediated by chemical messengers.
This chapter describes how these
messengers interact with their target
cells and how these interactions
trigger intracellular chains of
chemical events that lead to the
cell’s response. Throughout this
chapter, the reader should carefully
distinguish
inter
cellular (between
cells) and
intra
cellular (within
a cell) chemical messengers and
communication. The material in this
chapter will provide a foundation
for understanding how the nervous,
endocrine, and other organ systems
work.
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